The adaptive process, set as the program of actions by the regulator centres, is accompanied by mobilization of the visceral systems providing the physiological price and result. Research of catecholamines by separate parts discloses local mechanisms of regulation. At the same time functional activity of an organism is achieved owing to integrative processes. From this point of view studying the general metabolism - adrenaline and noradrenaline is justified.
The symphato-adrenal system excreting catecholamines - noradrenaline and adrenaline - is of great importance for the adaptation of a growing organism to conditions of environment. It carries out its regulator influence on functions of an organism through hormonal mediators which, according to L.A. Orbeli, promote a constancy of the internal environment and its adaptation to varied conditions of life.
At present the significant amount of works has been published which discover the dynamics of excretion of catecholamines and their predecessors in children basically of teenage age, including those with academic and physical loadings.
According to our data, excretion of adrenaline and noradrenaline in urine in children in the age of 6-8 years undergoes the wavy dynamics in both sexual groups, with the greatest expressiveness in boys in the age of 6 and 7 years. Judging from excretion of adrenaline and noradrenaline in urine, the character of synthesis and utilization of catecholamines varies essentially. In this age interval, the chronotropic function of heart is appreciably reconstructed. Physiological preconditions of this age form the adequate mechanisms of urgent adaptation influencing behavioral activity.
Our researches have shown that boys adapt more difficultly for conditions of school: within one academic year the exhaustion dependent on a sex and age of the child develops in children. During educational occupations children in the age of 6-8 years show the changes reflecting a functional condition of an organism. The character and intensity of these changes serve a mark of "physiological cost" of academic load.
The work was submitted to III international scientific conference «Basic Research», Dominican Republic, April, 10-20, 2008, came to the editorial office 19.01.2008.