Scientific journal
European Journal of Natural History
ISSN 2073-4972
ИФ РИНЦ = 0,301

SOME PROBLEMS IN COMPUTER RECONSTRUCTION OF ORGANS, TISSUES AND CELLS IN HUMAN AND ANIMAL MORPHOLOGY

Pavlovich E.R., Prosvirnin A.V., Pistsova T.V., Fedoseev V.A.

Modern computer equipment allows us to create 3-D models of methodical - biological objects that find a wide implementation in typographic anatomy and surgery, as well as in computer tomography of diagnosis purposes (Maykaya, 2000; Blinov, 2005). Along with that another area of medical science exists, in which a work with visual images goes on that could make a breakthrough in our knowledge of human and animals organ, tissue, and cells structure. It is the morphology that includes anatomy, histology, and cytology. It could allow us to carry out a multi-level reconstruction of organs and their components. This knowledge was especially important for defining anatomic, histological, and cytological peculiarities of various knots and tracts distribution in heart, where significant blanks in topographic determination of all the organ´s leading systems and its nervous and vascular components exist. It leads to the fermentation of our knowledge on the organ´s function morphological substance in its normal and pathological condition. Classical heart leading systems and knot operative myocardium metastructure reconstruction methods are very rare to find in literature (Thaemert, 1978) because of their laboriousness and significant technical difficulties (a cutting of serial ultrathin cuts on numerous nets of one block takes years of work). We can try to make the researcher´s problems easier if we use little animal organs enclosed in one block of epoxy gums and further its cutting into thick (50-100 mcm) cuts, then half-thin (1-2 mcm) cuts, and, if necessary, from them - into ultrathin cuts (50-70 nm). Further, as we obtain analog pictures, we can try, using a perspective, to form a single image (like it is done in animation). Or, as we digitize a cut series, we can obtain the same result if we use a 3D graphic editor. It should be outlined that special program products for metastructure and histological pictures analysis are extremely rare and expensive, and their development requires work of competent programmers along with the labor of morphologists. Structure modeling, first of all, of inner muscular organs (heart, uterus) with the usage of serial half-thin and thick cuts will allow us to define the layer organs structure and then will reveal functionally-important part of these organs (for example, sphincters, nerve ganglions, leading ways). An involvement of cybernetics students of RCSPC medical-biological faculty will aim them for the development of program applications that can be used in future to reconstruct all the various mammal types organs, including those in normal ontogeny and under various pathologies. Besides, it will, if provided with the digital organ model, to rotate it in different angles and reveal the peculiarities of its tissue, cellular, and subcellular structure.


The work was submitted for the International Scientific Conference «Computer modeling in science and techniques», Andorra, 9-16th of March, 2011, came to the editorial office оn 03.02.2011.