Scientific journal
European Journal of Natural History
ISSN 2073-4972
ИФ РИНЦ = 0,301

ENZYMES OF ANTIOXIDATIVE DEFENSE IN PIG BLOOD

Dementyev A.V.

An organism responds to stress by a standard response-stress. This is the process connected with homeostasis regeneration and vitality maintenance. The process increases activity of regulatory stress-system that makes organs and tissues involved function under altered conditions.

As a result, the stress-system activation intensifies the discharge of stress-hormones into blood. The primary messengers are followed by a cascade of biochemical reactions that encourage mobilization of an organism to respond to the action of a certain stressor. Xanthine oxidase facilitates the formation of oxygen intermediates under oxidative stress. They realize oxidizing modification of lipids. Antioxidative defense prevents changes in the lipids structure. Catalase, peroxidase, etc., are referred to the enzymatic link of the antioxidative defense. They break down hydrogen dioxide having been formed under the oxidative stress.

The research was carried out at Open Joint Stock «Landrace» in Novosibirsk region. Landrace pigs were the object of the research. The animals were selected to be grouped following the principle of analogues with regard to origin, breed, productivity, age and live weight. The pigs were kept in accordance with the technology for complexes and farms. Blood to examine was taken from aural vein. The activity of xanthine oxidase was examined in blood serum of pigs aged 1, 2, 3, 4, 5 and 6 months. The data obtained was processed statistically with the package of applied software Statistica 6 and Excel.

Age changes in the activity of the examined enzymes were revealed in the blood of Landrace pigs. Significant increase in the peroxidase activity was identified in the blood of gilts aged 5 months (54,01 ± 1,62 c.u, p < 0,001). At this age period catalase activity was high enough, but xanthine oxidase activity was low. The data obtained testifies to the protective effect of catalase and peroxidase under the oxidative stress and their activity may be the evidence of the oxidative stress process running.


The work is submitted to the International Scientific Conference «Fundamental research», Dominican Republic, April 13-24, 2011, came to the editorial office оn 19.01.2011.