Scientific journal
European Journal of Natural History
ISSN 2073-4972

THE FREQUENCY OF ASSOCIATED PATHOLOGY OF GASTROINTESTINAL TRACT OF THE PATIENTS WITH THE GASTROESOPHAGEAL REFLUX DISEASE

Loginov S.V., Koslova I.V., Golovchenko S.V., Denisova O.I.
The aim of research: to reveal the frequency of association of gastroesophageal reflux disease (GERD) with other diseases of gastrointestinal tract (GIT).

Materials and methods: there were examined 115 patients with the GERD, their average age were 427,6, from them 36 women and 76 men. The criterion of including to the research was the presence of nonerosive or erosive GERD. Patients went through the standard examination which includes fiberoptic esophagogastroduodenoscopy (EGD) with the morphological verification of diagnosis, radioscopy of esophagogastroduodenal region, ultrasonic research of abdominal organs (ultrasonic examination of abdominal organs), diagnosis of infection Helicobacter pylori (HP) was carried out by means of urease breath test and histobacterioscopic, the examination of bowel included lower gastrointestinal series and/or colonoscopy.

Results: It was established that I 90 cases (78,3%) GERD was combined with the chronic gastritis (CG). The structure of CH while the EGD occurred with the following way: 25 patients (27,8%) had the focal atrophic gastritis, 2 patients (2,2%) had the total atrophic gastritis, 42 patients (46,7%) had the catarrhal gastritis, 21 patients (23,3%) had the erosive gastritis. 35 patients (30,4%) had GERD associated with the ulcerous disease (UD), and in 33 cases (94,3%) there was diagnosed UD of duodenum, in 2 cases (5,7%) - UD of stomach. 75 patients (65,2%) had GERD combined with the chronic pancreatitis, 20 patients (17,4%) with the GERD had chronic cholecystitis, 30 patients (26,1%) with the GERD had chronic nonspecific colitis, 65 patients (56,5%) with the GERD had the infection Helicobacter pylori. Besides, in 30 cases (26,1%) GERD was associated with the hernia of esophageal opening of diaphragm, in 45 cases (50%) - with the antro-pyloric duodenal discoordination, in 40 cases (34,8%) - with the anomalies of form of gall bladder.

Conclusion: received facts demonstrate the most frequent associations of gastroesophageal reflux disease with the chronic gastritis and pancreatitis, helicobacteriosis, markers of undifferentiated dysplasia of connective tissue of gastrointestinal tract (the hernia of esophageal opening of diaphragm, antro-pyloric duodenal discoordination, anomaly of gall bladder form.


The work is submitted to Scientific Conference "The Problems of International Integration of Educational Standards", England (London) - France (Paris), 23 April -1 May, 2010. Came to the Editor´s Office on 11.02.2010.